Nephrotoxicity of vancomycin in patients with normal serum creatinine.
نویسندگان
چکیده
Chronic renal disease is frequent in the general population. In the case of epidemia or pandemia of avian influenza A (H5N1), the two neuraminidase inhibitors, oseltamivir and zanamivir will therefore be used in patients with renal impairment. Although zanamivir does not necessitate any adjustment of its dosage in patients with renal failure, because it is not absorbed after oral inhalation, oseltamivir dosage must be reduced by half in patients with CrCl between 15 and 30ml/min and may be used at the usual dose when CrCl is higher.
منابع مشابه
Incidence and Predisposing Factors of Vancomycin-Induced Nephrotoxicity in Children
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Vancomycin susceptibility of methicillin-resistant Staphylococcus aureus has been changed over time and its average minimum inhibitory concentration increased from 1.5 to 1.75 mg/L. A recently published guideline by the American Society of Health Pharmacist recommended a daily dose of 15-20 mg/kg every 8 to 12 hours of vancomycin to achieve a trough concentration between 15-20 mg/L for treatmen...
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عنوان ژورنال:
- Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association
دوره 21 12 شماره
صفحات -
تاریخ انتشار 2006